In the United Kingdom, 'In My Head' debuted at the top of the UK Singles Chart on Febru– for the week ending date Ma– making it Derulo's first chart-topping song in Britain and second consecutive top 10 hit there. It has been certified 7× Platinum in Australia, making it one of the country's best-selling singles of all time.

In Australia, the song peaked at the top of the ARIA Singles Chart, and was the only song to debut at number one in Australia in 2010.

In Canada, the song peaked at number two on the Canadian Hot 100 in the issue dated March 13, 2010, becoming Derulo's second top three single in Canada. As of April 23, 2014, the single has sold over 3,174,000 digital copies, making it his second single to cross the 3 million mark.

On June 22, 2010, the song certified double platinum by the RIAA. It has since become Derulo's second song to reach the top 10, peaking at number five. 'In My Head' debuted on the Billboard Hot 100 at number 63 for the week ending December 26, 2009. The song was initially titled 'In My Bed', but Derulo and Kelly changed this to 'In My Head' at the last minute. The official remix features Nicki Minaj and was released on March 11, 2010.

He mentioned that the album displays both sides, so 'In My Head' was released to introduce his fans to the electronic side of the record. The song is electro-influenced and has a heavier rock feel than the R&B and electronica-influenced ' Whatcha Say'. Derulo has explained that 'In My Head' was chosen to be released as the second single from the album to show the other side of his debut album.

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